Given the development trajectory of the Mekong, one of the most needed technologies is data-driven dam operations coordinated across national boundaries. Professor John Sabo will discuss his work, which provides proof of concept for this intervention and its potential to sustain food security. More broadly, such data-driven approaches can be used to link hydrology to ecology and food production and specify design principles that could help to deliver food security in other river systems. Sabo is a professor of river ecology and water resources in the School of Life Sciences and founding director of Future H2O in the Office of Knowledge Enterprise Development at Arizona State University.